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The role ofmicrobiota-gut-brain axis in neuropsychiatric and neurological disorders

[DOI] [PubMed] [Google Scholar] 141.Pawliuk R., Westerman K.A., Fabry M.E., Payen E., Tighe R., Bouhassira E.E

Among 17,604 adults with overweight or obesity (BMI 27) and established cardiovascular disease but without diabetes, weekly semaglutide cut the primary composite of cardiovascular death, non-fatal heart attack or non-fatal stroke by about 20% reaching 6.5% of the semaglutide group versus 8.0% on placebo, a hazard ratio of 0.80 (95% CI 0.720.90) (PMID 37952131)

TB-500 cycles often follow a "loading and maintenance" pattern: a higher-frequency loading phase across the first weeks, then a lower-frequency maintenance phase