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Key findings include: Upregulation of VEGFR2 expression and internalization in endothelial cells Activation of the VEGFR2-Akt-eNOS signaling cascade Enhanced endothelial cell proliferation and tube formation Improved collateral circulation in ischemic injury models The peptides pro-angiogenic effects appear particularly relevant in healing scenarios where blood supply restoration is critical for tissue recovery

Presented at the 55th Americal Society of Haematology (ASH) Annual Meeting and Exposition 710 December 2013

The vaccine of claim 76, wherein the hMPV F polypeptide is a pre-fusion F polypeptide

These systemic reactions are also typically short-lived