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Tumor cells secrete galectin-1 to enhance endothelial cell activity

If you move from 0.5% to 1% to 2% in quick succession, you can't know which concentration was responsible for any observed improvements

In fact, FBP levels correlate with glycolytic flux 53,54 , and FBP is known to act as flux-signalling metabolite in multiple species ranging from bacteria to mammalian cells, transducing metabolic information into diverse cellular responses 55,56,57