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Ellagic acid (EA), a natural antioxidant, mitigates aging-related oxidative damage in the kidney by upregulating the mRNA and protein expression of SIRT1 and NRF2, while also promoting the deacetylation of NRF2 protein [70]

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Haddad JJ, Saad NE, Safieh-Garabedian B: Redox regulation of TNF- biosynthesis: Augmentation by irreversible inhibition of -glutamylcysteine synthetase and the involvement of an IB-/NF-B-independent pathway in alveolar epithelial cells