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as well as chronic pathophysiological sequelae in virus-free COVID-19 survivors the long-COVID or PASC patients

doi: 10.1016/j.jnutbio.2007.05.006 85 MottaL

Mutations in these genes are linked to the regulation of amyloid-beta processing, a crucial component of AD pathogenesis

This decline results from increased consumption by CD38 (which rises with chronic inflammation), decreased synthesis via the NAMPT salvage pathway, and accumulated DNA damage driving PARP activation