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SKU: 7499853422
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Description

Enzymatic activity of this complex has been found to be compromised in PD patients, but to date it has not been clear how this inhibition occurs

2h), giving further evidence of the importance of free GSH for catalysis

Tibotec Therapeutics

Given the essential role of SLC25A39 in mitochondrial glutathione transport, our results provide a mechanistic explanation for how SLC25A39 loss causes mitochondrial defects, neurodegeneration and anemia in yeast, flies and mice, respectively