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Lynch syndrome (LS), an autosomal dominant inherited cancer susceptibility syndrome, also known as hereditary non-polyposis colon cancer (HNPCC), is caused by a germline mutation in one of several DNA mismatch repair (MMR) genes: MLH1, MSH2, MSH6 or PMS2

In addition, glucocorticoids in breast milk (cortisol and its inactive form cortisone) are closely linked to signaling pathways for processes such as energy balance, regulation of stress activity and immune function in the infant [17]

We would like to thank Shanghai Applied Protein Technology for the measurements and basic analysis of RNA-seq, and Editage ( for their assistance with English language editing

It works by blocking the enzyme tyrosinase from making melanin and protecting skin cells from damage caused by free radicals