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Comparison: MOTS-c + 5-Amino-1MQ Synergy vs Monotherapy Key Takeaways MOTS-c activates AMPK to increase mitochondrial function and fat oxidation, while 5-Amino-1MQ inhibits NNMT to preserve NAD+ poolstargeting complementary metabolic pathways

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The RNA sequencing analyses of rat enteric nervous cell PD model induced by rotenone showed that Mitogen-Activated Protein Kinase regulates the PD pathogenesis