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This is in qualitative agreement with our previous study using the same culture and CSE exposure approach where CS-induced changes were much more drastic on the transcript than on the protein level 30 (Online Supplement 2: Final Protein List)

Three things to never do with a reconstituted blend: never refreeze it, never store it in the refrigerator door (where temperature swings on every door open), and never expose it to direct sunlight

The fact that much of the research has been published by a relatively small number of teams, often in less demanding journals and without sufficient independent replication is definitely concerning. That said, he adds, there have been a few studies published outside of Croatia that report broadly similar findings, which is somewhat reassuring, though still not definitive

NNMT plays a role in a number of diseases/conditions makes development of NNMT inhibitors an important path to developing therapeutics to treat various diseases/conditions