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Cells were viewed under a fluorescence microscope

In individuals with overweight or obesity, treatment with semaglutide was associated with significant reductions in bodyweight, with a mean placebo-subtracted weight loss of 12.4% relative to placebo after 68 weeks reported in the STEP 1 trial

On testing days 4 and 5, the same procedure was followed, however, 30 min following the saline administration mice received an injection of either 1.2 or 2 g/kg ethanol (i.p., counterbalanced design) and were again placed in the open field for a 30-minute recording session

refrigerate the reconstituted solution and use within 2-4 weeks