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In 2021, Jung et al., in Korea, investigated whether the oral intake of enzymatically decomposed collagen peptides (acid-processed collagen peptides [APCPs]: 1000 mg suspended in 25-mL samples administered once per day) could improve skin moisture and barrier function by assessing changes in the ceramide and natural moisturizing factor (NMF) contents in the stratum corneum (SC), comparing baseline parameters to end-of-treatment parameter values [37]

cGMP-Prkg1 signaling and Pde5 inhibition shelter cochlear hair cells and hearing function

The damaging cycle then continues with A-induced downregulation of FPN and iron accumulation

Our findings may provide basic theoretical basis and experimental support for the discovery of effective targets or favorable factors for PAAD in clinical treatment and prognosis