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We also examined the hubs of the network built with the PPIs entered in first order and MPI in second order (2,593 nodes and 4,063 edges) and found that the top 3 hubs were in descending order of importance: NFKB1 (307), CTNNB1 (153), and ALB (152)

333,334 The gutkidney axis involves microbial orchestration with renal filtration, which threatens systemic health through circulatory and lymphatic conduits