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EPIC: A tool to estimate the proportions of different cell types from bulk gene expression data

5.5 Divergent roles of HO-1 in ferroptosis: between protection and promotion Although numerous studies have suggested that HO-1 may exert neuroprotective effects in VaD by regulating ferroptosis, an in-depth analysis of the existing literature reveals that the findings are not entirely consistent

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Consequently, these events result in diminished sperm production, interruption of hormone synthesis in the testes, and compromise of the blood testis barrier in Sertoli cells (Zhu et al., 2022)