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Abbreviations ACE2: Angiotensin-converting enzyme 2 AION: Anterior ischemic optic neuropathy AMD: Age-related macular degeneration AQP4: Antibodies targeting aquaporin-4 CNV: Choroidal neovascularization DR: Diabetic retinopathy EAU: Experimental autoimmune uveitis F/B: Firmicutes/Bacteroidetes FMT: Fecal microbiota transplantation GI: Glycemic index HLA-B27: Human leukocyte antigen B27 IgG: Immunoglobulin G IL-17: Interleukin-17 IOP: Intraocular pressure IRT5: Interphotoreceptor retinoid-binding protein fragment 5 LHON: Leber hereditary optic neuropathy LPS: Lipopolysaccharide MS: Multiple sclerosis NMOSD: Neuromyelitis optica spectrum disorder POAG: Primary open-angle glaucoma RCTs: Randomized controlled trials RPE: Retinal pigment epithelial SCFA: Short-chain fatty acid Th17: T helper 17 TLRs: Toll-like receptors TMAO: Trimethylamine N-oxide TNF-: Tumor necrosis factor-alpha Tregs: Regulatory T cells VKH: VogtKoyanagiHarada References Fan Y, Pedersen O (2021) Gut microbiota in human metabolic health and disease

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Additionally, there is an increase in RBC-MPs [413]