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This study was the only one that reported any significant cytotoxic effects of a PPI

This drug can cause fetal harm, but potential benefits may warrant use of this drug in some pregnant women

The most common side effects in people with metastatic colorectal carcinoma who take XELODA alone include: decreased red blood cell count diarrhea nausea hand and foot syndrome tiredness increased bilirubin level in your blood stomach-area (abdominal) pain The most common side effects in people with metastatic breast cancer who take XELODA in combination with docetaxel include: diarrhea hair loss swelling mouth sores or mouth inflammation hand and foot syndrome stomach-area (abdominal) pain nausea and vomiting The most common side effects in people with metastatic breast cancer who take XELODA alone include: decreased white blood cell and red blood cell count nausea and vomiting diarrhea tiredness hand and foot syndrome skin inflammation, including rash Severe allergic reactions can happen with XELODA

Immunohistochemistry analysis The colon samples were immediately fixed with 4% paraformaldehyde for 24 h upon separation, followed by paraffin embedding and cutting to a thickness of 4 m