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To test the possible increase in potency of the two drugs when given simultaneously, we injected a total volume of 4 ml of combined doses of L838,417 and CLP257 in a fixed dose ratio of \([{\mathrm{L 838,417]/[{\mathrm{CLP 257]\) = 1:55, given the relative EC50s of the two drugs calculated from the respective dose response curves with a priori assumption on the collapse at high doses of L838,417 (Fig

Truthmeter: 3 (out of 10) Truthmeter and contact info Fact Checker columns by Mark Robison are rated on a scale from 0 to 10, with 10 being absolutely true with no gray area, 5 being down the middle with good points by both sides, 1 being false with no gray area and 0 being intentionally, maliciously or foolishly false

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Genes Dev 27 , 24732488 (2013)