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Wan et al 2017: Impact of compound hypertonic saline solution on decompensated heart failure This is a single-center unblinded RCT in China involving 264 patients with systolic heart failure and refractory volume overload

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Corticosteroids Patients with UC and CD who do not achieve remission with 5-ASAs can be escalated to a more potent anti-inflammatory agent, such as corticosteroids

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an appropriate solute must be added first

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Neuron 20 , 103114 (1998)

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