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Johnson SL, Park HY, Vattem DA et al (2020) Equol, a blood-brain barrier permeable gut microbial metabolite of dietary isoflavone daidzein, exhibits neuroprotective effects against neurotoxins induced toxicity in human neuroblastoma SH-SY5Y cells and Caenorhabditis elegans

29 A statistical analysis of 17 randomized controlled trials that included a total of over 1,000 participants found that intake of probiotics, prebiotics (partially or completely indigestible carbohydrates that enhance growth of beneficial gut bacteria), or synbiotics (combinations of probiotics and prebiotics) was of benefit for metabolic aspects of PCOS