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The rationale for butyrate enemas in radiation proctitis is the same as for diversion colitis: radiation destroys the mucosal microenvironment, depletes butyrate-producing bacteria, impairs colonocyte energy metabolism, and compromises the barrier

Isoproterenol hydrochloride, which has physiological effects similar to those of the stimulating hormone epinephrine, is a powerful cardiac drug that could seriously harm or prove fatal if given by accident to a patient with an underlying heart condition

Moreover, higher iron content across cortical/subcortical gray matter and hippocampal subfields correlates with memory decrements even in cognitively normal older adults (Spence et al., 2022)

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