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Chapter 20 - Autophagy, oxidative stress, and redox regulation

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First we compare JNK inhibitors with a cyclohexenone/pentenone warhead scaffold with other formerly known open-chain Michael acceptor containing compounds and demonstrate that composite inhibitors with a cyclic warhead may have beneficial properties

In addition, encouraged by the aforementioned interesting applications of bioorthogonal ligation reactions, we suggest that this precise D2L strategy may be applied with inspiration to other important fields