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It was originally developed by a major pharmaceutical company and later tested in human trials for digestive recovery after surgery

[DOI] [PubMed] [Google Scholar] 347.Ismail M., Gromann D., Hermann A

The allocation of subjects to the three study arms and study design is shown in the CONSORT diagram (Figure 1)

The unchanged unwinding rate but elevated processivity is consistent with such an allosteric reduction in the helicase offrate rather than catalytic acceleration driven by such a Mer3-RPA constellation