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Bioconjugates of curcumin displayed improved neuroprotection activity (in terms of compensating the glutathione level) compared to curcumin [377]

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In non-angiogenic tumours the cells do not trigger angiogenesis but grow by exploiting the pre-existing vessels

288 By contrast, Parkin exhibits an oncogenic function in melanoma models, as its genetic ablation inhibits tumor growth and metastasis by destabilizing MFN2