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Lymphatic massage and manual lymph drainage have been shown to be especially effective in reducing the symptoms of edema

1419 (12,13)) and paracetamol (Plicet, Pliva)

These include 1) congenital pernicious anaemia, where there is a genetic defect in IF synthesis, leading to B12 malabsorption, 2) Imerslund-Grsbeck Syndrome (IGS) caused by mutations in genes encoding cubulin and amnionless , 3) inherited HC or TCII deficiencies, and 4) intracellular cobalamin defects (CblA-CblG defects)

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