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Glutathione Peroxidase 1 Promotes the Survival of Spiral Ganglion Neurons After Peroxynitrite Damage To clarify the role of GPX1 in the process of SGN injury caused by peroxynitrite, we performed experiments by increasing or inhibiting the expression of GPX1 in SGNs with the GPX1 mimic ebselen or using the gpx1 / mouse model

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Through inhibiting the conversion of T4 to T3 and enhancing the generation of rT3, Se shortage might impede the bodys capacity to adjust to certain stress situations, worsening the symptoms of hypothyroidism [6]

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