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McEwan, W

It's associated with an increased risk of AMD due to oxidative pathways and reduced intake of protective nutrients like Zn and vitamins

Hirano T, Ishihara K, Hibi M

The increased Bax/Bcl-2 ratio promotes mitochondrial outer membrane permeabilization and cytochrome c release, leading to the activation of caspase-9 and downstream executioner caspase-3 (78)