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(76) reported that grape seed PCs could inhibit phosphorylation events involving ERK, JNK, and p38 in human epidermal keratinocytes following UVB irradiation

Under oxidative stress, GSTP1-1 is auto-S-glutathionylated at residues Cys47 and Cys101, each of which affects the catalytic activity of the enzyme and its ability to bind target proteins

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Moreover, T cells upon stimulation downregulate GPX4 and upregulate ACSL4 that are both ferroptosis-promoting effects