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Not unusual, I thought, for a 12-year old dog

Cytotoxicity and radiosensitizing activity of the fatty acid synthase inhibitor C75 is enhanced by blocking fatty acid uptake in prostate cancer cells

Kang H-S, Ahn SH, Mishra SK, Hong K-M, Lee ES, Shin KH, et al

In this context, antifibrotic agents may represent a promising strategy for hypothyroidism-associated MAFLD, as they could counteract enhanced fibrogenic signaling while also exerting direct effects on ECM remodeling