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Introduction Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, has been reported, as of September 2022, in more than 600 million confirmed cases and has led to more than 6.4 million deaths worldwide ( While most COVID-19 patients will experience mild symptoms, some will develop severe acute respiratory distress syndrome, systemic inflammation, multiple organ failure, and other more serious complications that can lead to death

In the case of Zn(II) dissociation study without PAR initially, MT2 samples were first incubated with 80 M ajoene and allicin for a certain period of time, ranging from 5 to 120 min, before adding PAR to achieve a final concentration of 100 M

On the contrary, our observation of late-stage viral proteins (p24) in astrocytes contrasts with a previous study using neural organoids, which observed an absence of co-immunostaining of HIV gag and astrocyte markers 27