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Although CNTs have poor solubility in both water and organic media, they can be chemically modified to improve their solubility, degradation ability, and drug-loading capacity while reducing toxicity

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These cryogenic injuries are mainly attributed to osmotic stress, cold shock, intracellular ice formation, and the excessive generation of reactive oxygen species (ROS) during the freezing and thawing process 3

10.1016/j.fitote.2024.106344 90 QurbanF.ShahzadS