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Key Research Areas Cellular metabolism NNMT biology Energy regulation Enzyme activity 5-Amino-1MQ has attracted sustained scientific interest because of its association with nicotinamide N-methyltransferase (NNMT), an enzyme involved in cellular metabolism and the regulation of important biochemical pathways

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Patients affected by methylmalonic aciduria show cognitive impairment, and in mice, MMA accumulation in the brain causes neuroinflammation and oxidative stress injury (34)