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Dev Comp Immunol 39:3962 Acknowledgements The authors would like to acknowledge the support of the Biotechnology Lab., Faculty of Aquatic and Fisheries Sciences, Kafrelsheikh University, Egypt, where the laboratory investigations were carried out

Decreased short-chain fatty acids (SCFA) theory Gut hyperpermeability may also be linked to the by-products of amino acid fermentation, which produce SCFA [25]

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The untreated and MSO-treated parasite pellets isolated by saponin treatment were pooled separately during solubilization with 6 M urea in 25 mM ammonium bicarbonate buffer