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Acknowledgements The authors are grateful for the assistance of staff from the Experimental Animal Center and Analysis & Testing Center of Nanjing Medical University, Anhui Medical University, and Chungbuk National University

2020 Jan-Dec;19:1536012120952623

Exosome for mRNA delivery: strategies and therapeutic applications

Enhanced immune response by HOTTIP-induced polarization of local and circulating macrophages to the M1 phenotype also positioned macrophage-derived lncRNAs like HOTTIP as interesting candidates for individualized cancer immunotherapy ( Recent studies indicate that the best application of macrophage-derived lncRNAs to personalized oncology is through integration of immune and molecular signatures, but not as individual markers