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Additionally, curcumin actively inhibits COX-2 (cyclooxygenase-2) and LOX (lipoxygenase), the specific inflammatory enzymes that over-the-counter NSAIDs target to reduce pain and swelling, providing natural, systemic relief without the gastrointestinal toxicity associated with long-term NSAID use

Originally, BPC 157 appears as a cytoprotective antiulcer peptide, stable in human gastric juice, previously employed in ulcerative colitis clinical trials and now in those concerning multiple sclerosis (Sikiric et al., 1993

Acetaminophen and ibuprofen are preferred analgesics during lactation

Research protocols typically utilize: Low-dose protocols : 100-200 mcg of each peptide Moderate protocols : 200-300 mcg of each peptide Higher research doses : 300-500 mcg of each peptide Higher dosages correlate with increased side effect frequency and severity