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Neuropsychol Rev (2012) 22:7280

The antiapoptotic effect of DHEA is dose dependent with an EC50 at nanomolar concentrations (EC 50 : 11.23.6 nM and 12.42.2 nM in DU145 and Caco2 cells, respectively) [1]

Current researchers have identified quite a few other exogenous RTAs and many endogenous RTAs that play a role in iron-death-mediated diseases (e.g., Table 1)

A separately reported approach uses 1 mg daily for 20-day cycles 3-4 times per year totaling 20 mg per cycle, which is closer to the modified-form middle ground