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By inhibiting the ability of tumor cells to uptake glutamine and increasing the levels of glutamine within the tumor microenvironment, a dual effect can be achieved: suppressing tumor cell growth on one hand and enhancing the availability of glutamine for immune cells on the other hand, thereby strengthening the anti-tumor immune function of immune cells

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Glioblastoma (GBM), classified as a WHO IV glioma, is marked by its dismal prognosis, extensive tumor heterogeneity, and the absence of effective treatments, boasting a mere 5-year survival rate of 7.2% [1, 2]

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