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These elevated values were obtained even when highly specific and sensitive methodology based on immunoaffinity purification and stable isotope dilution LCMS was used Citation[134], which suggests that artifactual formation of 8-oxo-dGuo might occur during DNA isolation and hydrolysis Citation[144,154]

Liu Y, Zhao H, Zhang Q, Tang J, Li K, Xia XJ et al (2012) Prolonged dietary selenium deficiency or excess does not globally affect selenoprotein gene expression and/or protein production in various tissues of pigs

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Early Hum Dev (2012) 88(6):4214.10.1016/j.earlhumdev.2011.10.007 84 Tijerina-SaenzAInnisSMKittsDD