oral melanotic macule macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Intra oral photograph of the

[240] have recently shown that selenium can alleviate autistic behaviors in the BTBR mouse model of ASD by inhibiting ferroptosis via activation of the nuclear factor erythroid 2-related factor 2 (Nrf2)/GPX4 signaling pathway

In a 2003 study on multiple sclerosis patients, ALCAR supplementation for six months significantly increased glutathione levels in cerebrospinal fluid and reduced oxidative stress markers

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Subtle shifts in neurotransmitter tone or cellular energy status may influence vascular tone, sensory processing and pain pathways, creating a biologically plausible route by which ALCAR could alter headache susceptibility