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Neo-B12 Injection is also used to treat and prevent other forms of macrocytic anaemias caused by vitamin B12 deficiency, in which red blood cells that are larger than normal size result in a lack of haemoglobin

In vivo, hepatic knockdown of GADD45 in MCD-fed mice markedly reduced SIRT1 expression and the p-AMPK/AMPK ratio as shown by both western blotting and immunohistochemistry (Fig