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This enhancement was even more pronounced in the OGD/R + GO@GSH-RB group

Fe2+ participates in the Fenton reaction to form hydroxyl radical which reacts with lipids to form lipid peroxides

Current treatment methods are limited in their effectiveness and can only slow down disease progression, which highlights the urgency and importance of developing new treatment modalities to prevent or reverse the progression of CKD (Ruiz-Ortega et al., 2020)