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Therefore, considering a broad spectrum of effects that may result from the induction of NO synthesis, a deep analysis of its interaction with potent drugs affecting NO pathways should be performed (e.g., aspirin that has been shown to inhibit eNOS [ 57 ])

In cell and tissue models, Epithalon upregulates telomerase activity, maintains telomere length, and modulates aging-related gene expression (p16, p21) to delay senescence

111 In-labeled minigastrin (LEEEEEAYGWMDF), a CCK-2 receptor-selective peptide, has been employed to treat human colorectal and pancreatic tumors 70

Cold-inducible RNA-binding protein (CIRBP) adjusts clock-gene expression and REM-sleep recovery following sleep deprivation