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Results from the phase 2 TROPION-Lung05 trial published in the Journal of Clinical Oncology revealed that among 137 patients given 6 mg/kg of dato-DXd every 21 days for pretreated NSCLC, the confirmed ORR was 35.8% (95% CI, 27.8%-44.4%), including 32.8% of patients experiencing a partial response and 2.9% having a complete response

Herkenham M, Lee HY, Baker RA

In the prior-year quarter, the company reported earnings per share of $1.27

Tirzepatide vs semaglutide dosing Key differences : Tirzepatide : Dual agonist (GLP-1 + GIP) Higher starting dose (2.5mg vs 0.25mg) Faster titration schedule Typically higher maintenance dose Single agonist (GLP-1 only) Lower starting dose (0.25mg) Slower titration Lower maintenance dose Effectiveness : Tirzepatide produces 15-22% weight loss vs semaglutide's 15-17%