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Description

The role of PPAR and its cross-talk with CAR and LXR in obesity and atherosclerosis

In a Phase 2a trial, GSBR-1290 resulted in a significant weight loss of 6.2% after 12 weeks, outperforming the placebo group

2018;7(3): e1395997

Adipose tissue in SAT diseases is resistant to loss by usual measures including extreme dietary changes (both hypocaloric and in macronutrient content) and exercise