glutathione peroxidase 4 gpx4 gsh Therapeutic approach of glutathione/glutathione peroxidase-4

Autoimmune diseases affect up to 10% of adults and are on the rise

On the other hand, there is evidence that the immune response to less damaging pathogens may produce a more severe reaction than the original infection

Treatment strategies aiming to interfere with the formation of amyloid (A) plaques and neurofibrillary tangles (NFTs), the two major AD hallmarks, have shown modest or no effect

In addition, similar liposomal entrapment is applied to the nucleic acid-based drugs, with additional enrichment of nucleic acid entrapment by addition of a cationic derivative of cholesterol (DC-Choi) to the liposomes, as detailed in Gao and Huang, 1991, Biochem Biophys Res Commun