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Classification and structure The superfamily of the glutathione transferases are divided into at least four major families of proteins, namely cytosolic or soluble GSTs, mitochondrial GSTs, microsomal GSTs and bacterial fosfomycin-resistance proteins [39], [6], [69]

This further suggests that significant activation of the NRF2/SLC7A11/GSH pathway may occur only when DRP1 is in its active form or directly activated

The staining was performed according to manufacturers instructions and images were acquired with a Zeiss Axiovert 200 M microscope

This article reviews the role of various antioxidants on AD progression and describes the mechanistic role of such substances on the nervous system