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L., Menndez, S., Len, R., Chang, S., Guanche, D., Balbn, A., Garca, P

Additionally, lipids having mixtures of saturated and unsaturated fatty acid chains can be used

For HIF transcription factors, this occurs by hydroxylation at conserved proline residues by prolyl hydroxylases under normoxia, allowing their recognition and ubiquitination by the VHL E3 ubiquitin ligase, which targets HIFs for proteasomal degradation