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The authors proposed multiple potential mechanisms including interactions with opioid, GABAergic, and monoaminergic systems, establishing the conceptual framework for subsequent mechanistic research into DSIP's neurophysiological actions

Animal-Model Research: What's Actually Been Studied The research base for BPC-157 is predominantly pre-clinical in-vitro cell studies and animal-model experiments, predominantly in rodent models

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The mean frequency of AMPA- mediated mEPSCs recorded from vehicle treated neurons was 3,06 0.23 Hz from 33 celts while Nle'-AnglV induced a 1.7 fold increase (5.27 0.43 Hz from 25 cells