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321,322 The lncRNA GATA6-AS1 has been shown to interact with transglutaminase 2 (TGM2), resulting in changes in mitochondrial function, promoting the restoration of damaged intestinal mucosal epithelial function and mucosal healing, and improving the prognosis of UC

This often affects older adults, who are more likely to experience a decline in stomach acid

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Preclinical studies suggest ALA may help defend neurons against oxidative stress, support synaptic function, and maintain healthy levels of glutathione, a critical antioxidant in brain cells.12 25 Importantly, ALA can cross the blood-brain barrier, making it a promising candidate for addressing conditions where oxidative stress or mitochondrial dysfunction play a role