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2014 Mar;24(3):22435

Evaluation of melon seed oil Citrullus colocynthis (L.) Schrad, for the protection of cowpea Vigna unguiculata seeds against Callosobruchus maculatus (Fabricius) (Coleoptera: Bruchidae)

Research indicates that the IGF-1 signaling pathway enhances mitochondrial antioxidant capacity, reduces ROS generation, and promotes mitochondrial DNA repair by activating the downstream PI3K/Akt pathway ( The mechanism of oxidative damage caused by IR to the organism is shown in Figure 2