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514 UPR signaling in neuroinflammation, oligodendrocyte survival, and demyelination in MS ER stress is widely observed in demyelinating lesions in MS, with elevated levels of markers such as CHOP, BiP, phosphorylated PERK, phosphorylated eIF2, and XBP-1 in microglia, oligodendrocytes (OLs), T cells, and astrocytes

Important Safety Information Do not use AOD-9604 if you: Have a known allergy to growth hormone fragments or any component of the formulation Have been diagnosed with active cancer or have a history of malignancy (use only under medical supervision) Are pregnant or breastfeeding (safety data is lacking) Have severe uncontrolled diabetes or metabolic disorders without medical supervision Common side effects may include: Injection site reactions, mild headaches, temporary fatigue, or slight dizziness during initial use

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If a claim implies systemic benefits, treat it as a higher-uncertainty category and prioritise evidence quality over confidence