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For instance, a size-dependent study of surface-modified poly(lactic-co-glycolic acid) (PLGA) nanoparticles demonstrated that particles with the smallest size (60 nm) exhibited the highest brain accumulation compared with larger particles, suggesting that smaller nanoparticles traverse the BBB more efficiently than larger particles (Meng et al., 2022)

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Next, we sought to identify the RCMVEencoded factor responsible for the reduction of STAT2 levels

it is essential for healing yet can result in prolonged tissue damage if it persists excessively